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Suspected normal pressure hydrocephalus

ACR AC Dementia (2024 update); NPH imaging literature

The imaging question is not simply whether the ventricles are large — it is whether they are large out of proportion to atrophy, which is a pattern judgement that MRI supports and a report of "ventriculomegaly" does not.

Older patient with the triad of a magnetic gait, cognitive slowing and urinary urgency, where a potentially treatable cause of decline is being sought.

Referenced decision support — confirm against your local protocol.

Decision support, not a directive. Protocols and timings shown are typical published ones — your local protocol takes precedence, and the vetting radiologist decides.

The request in front of you

Everything is optional. Leave a field alone and the answer assumes nothing — the verdict updates as you go.

Study requested

What the referrer actually asked for. It is evidence of intent, not a constraint on the right answer.

Contrast as written

What the request form says, not what it should say.

Age

Pick a band, or type an exact age if it matters.

years
Pregnancy status
Renal risk factors

The question a vetter can actually answer from the request. An explicit “none known” is a real answer, and it removes checks rather than deferring them.

Previous contrast reaction
The pathway — tap anything already done

Marking a study complete moves the answer on. A patient arrives partway through a pathway far more often than at the start of one.

Accept as requested
MRI Brain — routine unenhanced
MRI Brain
What we'd amend, and why
  • The diagnosis depends on comparing ventricular size against cortical sulcal volume in defined places, and on a mid-sagittal measurement of the callosal angle — neither of which is reliable on axial CT sections angled variably to the skull base. MRI additionally shows the aqueduct and the posterior fossa, distinguishing a communicating pattern from an obstructive one, and grades the coexisting small vessel disease and medial temporal atrophy that predict a poor response to shunting.

Nothing needs resolving before this goes ahead. Routine checks below are owned downstream.

How was this decided?
  1. pathwayadult — Adults
  2. rulerule-mr-device-screening — MR safety screening for implants and foreign bodies; checked by Radiographer at the scanner
  3. rulerule-paeds-sedation — Sedation or anaesthesia for a child; checked by Nurse before the scan

Decision support only. Local protocol takes precedence.

Handled at the scanner(1)nothing for you to do

Settled and owned downstream. Each returns to a radiologist only on the stated trigger.

  • MR safety screening for implants and foreign bodies
    Complete the MR safety questionnaire, verify implant labelling and its stated conditions of use against this scanner and this protocol, and ensure no ferromagnetic object enters Zone IV.
    Radiographer at the scannerBefore the scan
    Flags back if: An implant or retained foreign body that is MR Unsafe, unlabelled, or cannot be identified; or an MR Conditional device whose stated conditions this scanner or the requested protocol cannot satisfy; or a credible unexcluded intraocular metallic foreign body history.

Pathways

Big forks are separate pathways; the first whose conditions match is the one used.

Adults

Matches your inputsDefault
RoleStudy & protocolWhy this answers the question
First line
MRI Brain
MRI Brain — routine unenhanced
usually appropriate
The diagnosis depends on comparing ventricular size against cortical sulcal volume in defined places, and on a mid-sagittal measurement of the callosal angle — neither of which is reliable on axial CT sections angled variably to the skull base. MRI additionally shows the aqueduct and the posterior fossa, distinguishing a communicating pattern from an obstructive one, and grades the coexisting small vessel disease and medial temporal atrophy that predict a poor response to shunting.
Reasonable alternative
CT Head
CT Head — Unenhanced
Acceptable where MRI cannot be tolerated or obtained, and it is the routine study for a suspected shunt malfunction in a patient who already has one. It can measure the Evans index and show gross disproportion, but it assesses the callosal angle and the convexity sulci poorly and misses the mimics that MRI would catch.

Pitfalls

  • Reporting ventriculomegaly without commenting on the proportion to atrophy, which is the only part of the finding that discriminates.
  • Relying on the Evans index alone. Its specificity is limited and it is measured differently by different observers.
  • Missing an obstructive cause at the aqueduct or in the posterior fossa, which turns a shunt discussion into a different operation.
  • Overlooking bilateral chronic subdural collections, which mimic the clinical triad and are treated by drainage rather than shunting.
  • Treating severe medial temporal atrophy and heavy small vessel disease as incidental — both predict a poor response to shunting and belong in the report.

Priors — what to pull first

  • Serial imaging is far more informative than a single study: progressive ventricular enlargement without progressive sulcal widening is the strongest radiological argument.
  • In a shunted patient, the baseline post-shunt scan is the comparator, not the pre-operative one.

What makes a good request

  • Ventriculomegaly is common in the elderly and most of it is atrophic. The distinguishing pattern is disproportionate enlargement of the ventricles with tight high convexity sulci and widened Sylvian fissures, together with a narrowed callosal angle.
  • Measurements are supportive rather than diagnostic. An Evans index above 0.3 is the conventional entry criterion, but it has poor specificity on its own and the diagnosis remains clinical plus radiological plus response to cerebrospinal fluid drainage.
  • The scan must also exclude the obstructive causes — aqueduct stenosis, a posterior fossa lesion, chronic subdural collections — which are managed completely differently.

How these studies are acquired

Contrast, phases and timing for every study on the pathways above.

Confirm locally

  • MRI Brain — routine unenhanced: timings are typical — confirm against local protocol.
  • Timings, contrast volumes and rates above are typical published values. Your department's protocol, scanner and patient population decide the actual numbers.
  • Safety thresholds and premedication policy follow local policy where it differs from the cited guidance.